| Item Type | Name |
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Concept
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Age Factors
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Concept
|
Algorithms
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Concept
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Blood Pressure
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Concept
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Alleles
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Concept
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Amino Acid Sequence
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Concept
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Antineoplastic Agents
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Concept
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Cell Line, Transformed
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Concept
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Antimetabolites, Antineoplastic
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Concept
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Antibodies, Monoclonal
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Concept
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Computer Simulation
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Concept
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Bayes Theorem
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Concept
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Cattle
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Concept
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Coenzyme A
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Concept
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Cell Adhesion
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Concept
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Cisplatin
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Concept
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Glucose-6-Phosphatase
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Concept
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Coronary Artery Disease
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Concept
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Diabetes Mellitus, Type 1
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Concept
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Diabetes Mellitus, Type 2
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Concept
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Dexamethasone
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Concept
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Insulin
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Concept
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Crohn Disease
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Concept
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Cyclophosphamide
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Concept
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Exons
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Concept
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Cytarabine
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Concept
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Introns
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Concept
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Microtubule-Associated Proteins
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Concept
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Genes
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Concept
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Fasting
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Concept
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Forced Expiratory Volume
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Concept
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Genetics, Population
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Concept
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Leukocytes, Mononuclear
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Concept
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Leukocytes
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Concept
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Pharmacogenetics
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Concept
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Microsomes, Liver
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Concept
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Nigeria
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Concept
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Feeding Behavior
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Concept
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Prostatic Neoplasms
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Concept
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Repressor Proteins
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Concept
|
Risk Factors
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Concept
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Cohort Studies
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Concept
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Japan
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Concept
|
Body Mass Index
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Concept
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Transcription, Genetic
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Concept
|
Software
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Concept
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Caenorhabditis elegans
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|
Concept
|
Cholesterol, LDL
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|
Concept
|
Trans-Activators
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|
Concept
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Guanine Nucleotide Exchange Factors
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Concept
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Cell Adhesion Molecules
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Concept
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Inflammatory Bowel Diseases
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Concept
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Leukemia, Myeloid, Acute
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Concept
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Causality
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Concept
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Paclitaxel
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Concept
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Gene Expression
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Concept
|
Comorbidity
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|
Concept
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Case-Control Studies
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|
Concept
|
Human Genome Project
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|
Concept
|
RNA Interference
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Concept
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Ecosystem
|
|
Concept
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Endometrial Neoplasms
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Concept
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Ubiquitin Thiolesterase
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Concept
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Cell Proliferation
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Concept
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Genes, X-Linked
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|
Concept
|
ras Proteins
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|
Concept
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Antineoplastic Agents, Alkylating
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|
Concept
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Cytochrome P-450 CYP2D6
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|
Concept
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Antineoplastic Agents, Hormonal
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|
Concept
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Prefrontal Cortex
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|
Concept
|
Systems Biology
|
|
Concept
|
Proteomics
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Concept
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Cortactin
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Concept
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Biological Specimen Banks
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Concept
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Genomic Imprinting
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|
Concept
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Budesonide
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|
Concept
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Cell Growth Processes
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|
Concept
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3' Untranslated Regions
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|
Concept
|
Platinum
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|
Concept
|
Promoter Regions, Genetic
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|
Concept
|
Glycemic Index
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|
Concept
|
HEK293 Cells
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|
Concept
|
Adaptor Proteins, Signal Transducing
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|
Concept
|
Survival Rate
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|
Concept
|
Argonaute Proteins
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|
Concept
|
ATP-Binding Cassette Transporters
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|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Cation Transport Proteins
|
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
|
Concept
|
Transcriptome
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
Metabolomics
|
|
Concept
|
Molecular Sequence Annotation
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|
Concept
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Cell Line, Tumor
|
|
Concept
|
Brain Neoplasms
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|
Concept
|
Cell Line
|
|
Concept
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Clinical Trials as Topic
|
|
Concept
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Data Interpretation, Statistical
|
|
Concept
|
Deoxycytidine
|
|
Concept
|
Drug Screening Assays, Antitumor
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|
Concept
|
Longitudinal Studies
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|
Concept
|
Lymphocyte Activation
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|
Concept
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Lymphocytes
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Concept
|
Retrospective Studies
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|
Concept
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Age of Onset
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|
Concept
|
Computational Biology
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|
Concept
|
Genetic Predisposition to Disease
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|
Concept
|
Genomics
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|
Concept
|
Rare Diseases
|
|
Concept
|
Quantitative Trait Loci
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Concept
|
Chromosomes, Human, X
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Concept
|
Genetic Loci
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Concept
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HapMap Project
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Academic Article
|
Accounting for animal movement in estimation of resource selection functions: sampling and data analysis.
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Academic Article
|
Population differences in microRNA expression and biological implications.
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Academic Article
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Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
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Academic Article
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Exprtarget: an integrative approach to predicting human microRNA targets.
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Academic Article
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Functional consequences of PRPF39 on distant genes and cisplatin sensitivity.
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|
Academic Article
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On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy.
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|
Academic Article
|
Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.
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|
Academic Article
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Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.
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|
Academic Article
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Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
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|
Academic Article
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An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers.
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Academic Article
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Identification of novel germline polymorphisms governing capecitabine sensitivity.
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|
Academic Article
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Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
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|
Academic Article
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Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel.
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|
Academic Article
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Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.
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|
Academic Article
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Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
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|
Academic Article
|
Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival.
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|
Academic Article
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Integrative genomics: quantifying significance of phenotype-genotype relationships from multiple sources of high-throughput data.
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Academic Article
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Genome-wide interrogation of longitudinal FEV1 in children with asthma.
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|
Academic Article
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The impact of microRNA expression on cellular proliferation.
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|
Academic Article
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Poly-omic prediction of complex traits: OmicKriging.
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|
Academic Article
|
Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity.
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|
Academic Article
|
Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation.
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|
Academic Article
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Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.
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|
Academic Article
|
Genetic and epigenetic variants contributing to clofarabine cytotoxicity.
|
|
Academic Article
|
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
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|
Academic Article
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Quantitative allelic test--a fast test for very large association studies.
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|
Academic Article
|
EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.
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|
Academic Article
|
Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
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|
Academic Article
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Association of body mass index and outcomes after major lung resection.
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|
Academic Article
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Pleiotropic genes for metabolic syndrome and inflammation.
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|
Academic Article
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Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
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|
Academic Article
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MicroRNA biogenesis and cellular proliferation.
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|
Academic Article
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A gene-based association method for mapping traits using reference transcriptome data.
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|
Academic Article
|
C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
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|
Academic Article
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Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.
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|
Academic Article
|
The genetic architecture of type 2 diabetes.
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|
Academic Article
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Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.
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|
Academic Article
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
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|
Academic Article
|
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
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|
Academic Article
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Annotation-free quantification of RNA splicing using LeafCutter.
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|
Academic Article
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
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|
Academic Article
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ukbREST: efficient and streamlined data access for reproducible research in large biobanks.
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|
Academic Article
|
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Academic Article
|
Genetic architecture of gene expression traits across diverse populations.
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|
Academic Article
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Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans.
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|
Academic Article
|
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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|
Academic Article
|
A multi-stage genome-wide association study of uterine fibroids in African Americans.
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|
Academic Article
|
Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer.
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Academic Article
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A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.
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Academic Article
|
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.
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Academic Article
|
Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample.
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Academic Article
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Integrating predicted transcriptome from multiple tissues improves association detection.
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Academic Article
|
Opportunities and challenges for transcriptome-wide association studies.
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Academic Article
|
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
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Academic Article
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Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits.
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Academic Article
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Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
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Academic Article
|
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
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Academic Article
|
A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.
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Academic Article
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Genetic regulatory variation in populations informs transcriptome analysis in rare disease.
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Academic Article
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Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts.
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Academic Article
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CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses.
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Academic Article
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PhenomeXcan: Mapping the genome to the phenome through the transcriptome.
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Academic Article
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sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression.
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Academic Article
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Cell type-specific genetic regulation of gene expression across human tissues.
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Academic Article
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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx.
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Academic Article
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The impact of sex on gene expression across human tissues.
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Academic Article
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Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification.
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Academic Article
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Transcriptomic signatures across human tissues identify functional rare genetic variation.
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Academic Article
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Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations.
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Academic Article
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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.
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|
Academic Article
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A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction.
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Academic Article
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Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.
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Academic Article
|
Transcriptome prediction performance across machine learning models and diverse ancestries.
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|
Academic Article
|
Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer.
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Academic Article
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Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries.
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Academic Article
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Protein prediction for trait mapping in diverse populations.
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Academic Article
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Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
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Academic Article
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Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.
|
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Academic Article
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Discerning asthma endotypes through comorbidity mapping.
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Academic Article
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Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits.
|
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Academic Article
|
Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations.
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Concept
|
Glucagon-Like Peptide-1 Receptor
|
|
Concept
|
Capecitabine
|
|
Concept
|
Machine Learning
|
|
Concept
|
Ubiquitin-Specific Peptidase 7
|
|
Academic Article
|
A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes.
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Academic Article
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Predicted Proteome Association Studies of Breast, Prostate, Ovarian, and Endometrial Cancers Implicate Plasma Protein Regulation in Cancer Susceptibility.
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Academic Article
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Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation.
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Academic Article
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Revealing polygenic pleiotropy using genetic risk scores for asthma.
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Academic Article
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Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations.
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Academic Article
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On the problem of inflation in transcriptome-wide association studies.
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Academic Article
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Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits.
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